FYP1 Logbook

My weekly update for FYP1 entitled Fabrication and Morphological Characterization of Electrospun Cellulose Acetate Nanofibers Loaded with Temozolomide for Brain Tumor Drug Delivery

My Supervisor: Dr. Mohamad Ikhwan bin Jamaludin

Week 1

FYP1 Briefing

- Facilitator : Dr Mohamad Ikhwan bin Jamaludin

Contents : 

- Introduction to FYP1 website

- Flow of FYP1 process

- Aims of FYP1

- FYP1 mark distribution

- Logbook and Turnitin

Week 4

Continue Updating Contents of Background Study and Background of Project

Contents :

- Refine the background study

- Adding new articles and review papers into Mendeley for reference

- Background of project : Application of cellulose acetate in biomedical field, effect of incorporation of nanoparticles on nanofibers

Week 7

Updating Progress of Literature Review

Contents :

- Adding new contents to literature review

- Searching for new references

Week 10

Trial and Error for Experiment

Date : 11/12/2023

Contents :

- 2.04g CA powder

- 12 ml of acetone, ethanol and dimethylacetamide (DMAc) in 3:1:2 ratio

- Mixing using magnetic stirrer in an enclosed bottle at room temperature for 6 hours

- TMZ will be added using different weights,  5 mg, 10 mg and 15 mg

- 11 kV, 0.5 ml/hr

- SEM images to observe the fiber distribution

Week 13

Obtaining preliminary results

Date : 31/12/2023

Contents :

- SEM images for electrospun pristine CA nanofibers produced under parameters of :

   i) 11 kV, 0.5 ml/hr

   ii) 11 kV, 0.7 ml/hr

   iii) 11 kV, 1.0 ml/hr

   iv) 18 kV. 0.5 ml/hr

   v) 21 kV, 0.5 ml/hr

- SEM images show inconsistent diameters of electrospun nanofibers

- Still need adjustments to obtain consistent diameters of the pristine CA nanofibers

photo_2024-01-08_21-18-51.jpg

Week 2

Introduction to Research Methodology for FYP1 Part 1

- Date : 17/10/2023

- Facilitator : Dr Mohamad Ikhwan bin Jamaludin

Contents : 

- How to write proposal in thesis format

- 5 chapters : Introduction, Literature Review, Methodology, Results and Discussion, Summary/Conclusion

- Introduction : Background study, problem statement, research objectives, scope of study, significance of study

- Literature review : Background of project, objectives

- Methodology : Method used for each objective

Supervisor Meeting

- Date : 18/10/2023

- Supervisor : Dr Ikhwan bin Jamaludin

Contents :

- In depth discussion regarding chapter 1 and chapter 2 of thesis proposal

- Literature review : Advised sources to use = Scopus, Web of Science

- Introduction to Mendeley

- Tips and trick for FYP1

- How to use UTM Library for past articles/reports

Meeting 1 Dr Ikhwan.jpg

Week 5

Updating Progress of Literature Review

Contents :

- Searching for statistics relating to brain tumors

- Removing irrelevant references

- Paraphrasing ill-structured sentences

- Uploading proposal draft to show to supervisor next week

Week 8

Updating Progress of Literature Review (Mid Semester Break)

Contents : 

- Filling in contents related to literature review

- Finding images to illustrate the points mentioned in literature review

Week 11

Trial and Error for Experiment and Meeting with Supervisor

Contents :

- Preparation of pristine CA solution 

- Electrospinning of pristine CA nanofibers

- Learning how to operate the electrospinning setup

- Reminders :

   i) Always wear gloves while using any laboratory chemicals

   ii) Wear a lab coat

   iii) Use the fume cupboard when handling intense smelling chemicals

   iv) Wear gloves to avoid being electroshocked while handling the electrospinning components

 

photo_2024-01-08_21-19-48.jpg.1

Week 14

Proposal Thesis Writing

Contents :

- Chapter 1 : Introduction

- Chapter 2 : Literature review

- Chapter 3 : Methodology

- Chapter 4 : Expected results

- Chapter 5 : Conclusion

Week 3

Adding Progress to Proposal Contents

Contents :

- Research for background study : Describing details regarding brain tumors, properties of cellulose acetate and how its used for drug delivery

- Include citations when required

- Searching for articles of past studies/research regarding cellulose acetate nanofibers

 

Week 6

Meeting with Supervisor

- Date : 17/11/2023

Contents :

- Correcting unusual parts in proposal draft

- Statistics has to be included in both chapter 1 (Background Study and chapter 2 (Literature Review)

- Approximately 5 pages for chapter 1

- Background study : Include effectiveness of drug delivery, statistics and proposal's motivation

- Gantt chart : Include efforts for preliminary expected results

- Highlight main objective at the end of background studyphoto_2023-11-18_00-01-39.jpg

Week 9

Proposal Defense Briefing

Date : 26/12/2023

Contents :

- Reminder to update logbook

- Use UTM email for Turnitin

- Week 12 to submit slides

- Week 16 to submit proposal thesis

- Try to log into Turnitin and create a dummy file

- The expected results must align with project

- Remarks/Comments can be written during defense and be used to improve final proposal thesis

- Slide submission is done through Google Form by attaching Google Drive link

- Proposal defense is 10 minutes

 

Meeting with Supervisor

Date : 26/12/2023

Contents : 

- Rearranging parts in literature review to further fit the narrative

Week 12

Preparation for Proposal Defense

Date : 28/12/2023

Contents :

- Supervisor advised to combine literature review and introduction to shorten presentation time

- Describe the trend for statistics

- Go through the scope briefly, no need to go into detail

- Understand the concept for characterization

- Include images of setup in methodology

- Include past research images for expected results

- Relate conclusion with objectives

- Mock presentation done in front of supervisor

 

photo_2024-01-08_21-22-12.jpg